Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from <i>Alstonia scholaris</i>

doi:10.1021/acs.jnatprod.5c00027

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	Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris
	Zhu, Xu-Xin 1; Fan, Yao-Yue 2; Zheng, Cheng-Yu 2; Yang, Hong-Ying 1; Gao, Kun 1; Yue, Jian-Min1,2
	2025-03-14
发表期刊	JOURNAL OF NATURAL PRODUCTS (IF:3.885[JCR-2017],3.904[5-Year])
ISSN	0163-3864
卷号	88 期号:3 页码:815-820
摘要	Five complex indoline alkaloids, alstolarsines A-E (1-5) possessing two unprecedented carbon skeletons of 6/5/5/7/6/6(5) fused polycyclic systems, were isolated from Alstonia scholaris. Their structures were characterized using various methods including spectroscopic data, ECD spectra, and single-crystal X-ray diffraction. The inhibitory activities of alstolarsines A-D (1-4) on DRAK2 phosphorylation and ATP-citrate lyase were evaluated, but all of them were inactive.
WOS关键词	LEAVES
DOI	10.1021/acs.jnatprod.5c00027
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[21532007] ; National Natural Science Foundation of China[21772213] ; National Natural Science Foundation of China[2018ZX09711001-001-005] ; Drug Innovation Major Project of China[ZSTH-032] ; CAS[19QA1410800] ; Shanghai Rising-Star program Foundation (SCST)
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS记录号	WOS:001445757000001
出版者	AMER CHEMICAL SOC
引用统计	正在获取...
文献类型	期刊论文
条目标识符	http://119.78.100.183/handle/2S10ELR8/316672
专题	新药研究国家重点实验室
通讯作者	Gao, Kun; Yue, Jian-Min
作者单位	1.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
通讯作者单位	新药研究国家重点实验室
推荐引用方式 GB/T 7714	Zhu, Xu-Xin,Fan, Yao-Yue,Zheng, Cheng-Yu,et al. Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris[J]. JOURNAL OF NATURAL PRODUCTS,2025,88(3):815-820.
APA	Zhu, Xu-Xin,Fan, Yao-Yue,Zheng, Cheng-Yu,Yang, Hong-Ying,Gao, Kun,&Yue, Jian-Min.(2025).Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris.JOURNAL OF NATURAL PRODUCTS,88(3),815-820.
MLA	Zhu, Xu-Xin,et al."Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris".JOURNAL OF NATURAL PRODUCTS 88.3(2025):815-820.