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Anti-Inflammatory Salicin Derivatives from the Barks of Salix tetrasperma 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 16, 页码: 9215-9226
Authors:  Wu, Pei-Qian;  Li, Ying;  Ren, Yu-Hao;  Zhou, Jun-Su;  Liu, Qun-Fang;  Wu, Yan;  Yu, Jin-Hai;  Zhou, Bin;  Yue, Jian-Min
Favorite  |  View/Download：40/0  |  Submit date：2024/05/22
Salix tetrasperma  salicinderivatives  structural elucidation  anti-inflammatoryactivity  
Energy preservation for skeletal muscles: Shenqi Fuzheng injection prevents tissue wasting and restores bioenergetic profiles in a mouse model of chemotherapy-induced cachexia 期刊论文
PHYTOMEDICINE, 2024, 卷号: 125, 页码: 13
Authors:  Li, Wei;  Zhang, Zijia;  Berik, Entezar;  Liu, Yawen;  Pei, Wenqiang;  Chen, Sihan;  Wu, Wenyong;  Wang, Zhaojun;  Kong, Xinqin;  Long, Huali;  Lei, Min;  Wang, Jennifer Yiyang;  Li, Zhaoxia;  Liu, Liangfeng;  Hou, Jinjun;  Wu, Wanying;  Guo, De -an
Favorite  |  View/Download：64/0  |  Submit date：2024/04/09
Shenqi Fuzheng injection  Chemotherapy-induce cachexia  Bioenergetic profiles  Glycolysis  TCA cycle  lipid metabolism  
Shenqi Fuzheng injection alleviates chemotherapy-induced cachexia by restoring glucocorticoid signaling in hypothalamus 期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 3, 页码: 431-434
Authors:  Berik, Entezar;  Zhang, Zijia;  Li, Wei;  Liu, Yawen;  Chen, Sihan;  Wu, Wenyong;  Wang, Zhaojun;  Kong, Xinqin;  Pei, Wenqiang;  Dong, Huiqing;  Long, Huali;  Lei, Min;  Liu, Liangfeng;  Hou, Jinjun;  Feng, Jing;  Li, Zhaoxia;  Wu, Wanying;  Guo, De-an
Favorite  |  View/Download：74/0  |  Submit date：2024/06/27
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
Authors:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan;  Peng, Shao-Ping;  Yang, Yu-Mei;  Shu, Pan;  Li, Pei-Jin;  Li, Shan;  Hu, Hong-Lin;  Li, Qian;  Song, Lin-Lin;  Chen, Ke-Guang;  Zhou, Hai-Yan;  Zhang, Ye-Hui;  Zhao, Fu-Rong;  Tang, Bo-Hao;  Zhang, Wei;  Zhang, Xin-Fang;  Fu, Shu-Meng;  Hao, Guo-Xiang;  Zheng, Yi;  Shen, Jing-Shan;  Xu, Ye-Chun;  Jiang, Xiang-Rui;  Zhang, Lei-Ke;  Tang, Ren-Hong;  Zhao, Wei
Favorite  |  View/Download：67/0  |  Submit date：2023/12/11
COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects  
Amuc_1100 pretreatment alleviates acute pancreatitis in a mouse model through regulating gut microbiota and inhibiting inflammatory infiltration 期刊论文
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
Authors:  Wang, Li-juan;  Jin, Yuan-ling;  Pei, Wen-long;  Li, Jia-cong;  Zhang, Rui-lin;  Wang, Jia-ju;  Lin, Wei
Favorite  |  View/Download：51/0  |  Submit date：2024/01/16
acute pancreatitis  Amuc_1100  inflammation  gut microbiota  tryptophan metabolism  
Repurposed Fenoprofen Targeting SaeR Attenuates Staphylococcus aureus Virulence in Implant-Associated Infections 期刊论文
ACS CENTRAL SCIENCE, 2023, 页码: 20
Authors:  Jiang, Feng;  Chen, Yingjia;  Yu, Jinlong;  Zhang, Feiyang;  Liu, Qian;  He, Lei;  Musha, Hamushan;  Du, Jiafei;  Wang, Boyong;  Han, Pei;  Chen, Xiaohua;  Tang, Jin;  Li, Min;  Shen, Hao
Favorite  |  View/Download：52/0  |  Submit date：2023/10/17
Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity 期刊论文
ISCIENCE, 2023, 卷号: 26, 期号: 2, 页码: 27
Authors:  Wang, Rongjing;  Zhang, Yuchao;  Guo, Shiwei;  Pei, Siyu;  Guo, Wei;  Wu, Zhenchuan;  Wang, Hailong;  Wang, Minghui;  Li, Yizhe;  Zhu, Yufei;  Meng, Ling-Hua;  Lang, Jingyu;  Jin, Gang;  Xiao, Yichuan;  Hu, Landian;  Kong, Xiangyin
Favorite  |  View/Download：63/0  |  Submit date：2023/10/17
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors 期刊论文
PROTEIN & CELL, 2023, 卷号: 14, 期号: 1, 页码: 17-27
Authors:  Zang, Yi;  Su, Mingbo;  Wang, Qingxing;  Cheng, Xi;  Zhang, Wenru;  Zhao, Yao;  Chen, Tong;  Jiang, Yingyan;  Shen, Qiang;  Du, Juan;  Tan, Qiuxiang;  Wang, Peipei;  Gao, Lixin;  Jin, Zhenming;  Zhang, Mengmeng;  Li, Cong;  Zhu, Ya;  Feng, Bo;  Tang, Bixi;  Xie, Han;  Wang, Ming-Wei;  Zheng, Mingyue;  Pan, Xiaoyan;  Yang, Haitao;  Xu, Yechun;  Wu, Beili;  Zhang, Leike;  Rao, Zihe;  Yang, Xiuna;  Jiang, Hualiang;  Xiao, Gengfu;  Zhao, Qiang;  Li, Jia
Favorite  |  View/Download：60/0  |  Submit date：2024/03/27
high-throughput screening  SARS  CoV-2  main  papain-like  proteases  
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文
LEUKEMIA, 2022, 页码: 11
Authors:  Jiang, Kailong;  Li, Xuemei;  Wang, Chang;  Hu, Xiaobei;  Wang, Peipei;  Tong, Lexian;  Tu, Yutong;  Chen, Beijing;  Jin, Tingting;  Wang, Tao;  Wang, Hanlin;  Han, Yubing;  Gui, Renzhao;  Yang, Jianmin;  Liu, Tao;  Li, Jia;  Zhou, Yubo
Favorite  |  View/Download：95/0  |  Submit date：2023/04/10
Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection 期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8
Authors:  Zhang, Shihai;  Pei, Rongjuan;  Li, Meixia;  Su, Haixia;  Sun, Hao;  Ding, Yaqi;  Su, Minbo;  Huang, Chunfan;  Chen, Xia;  Du, Zhenyun;  Jin, Can;  Zang, Yi;  Li, Jia;  Xu, Yechun;  Chen, Xinwen;  Zhang, Bo;  Ding, Kan
Favorite  |  View/Download：78/0  |  Submit date：2021/12/16
COVID-19  SARS-CoV-2  Angiotensin converting enzyme 2 (ACE2)  3CL protease  Ecklonia kurome Okam  Polysaccharide  
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