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Multifunctional hydrogel dressing composed of trichosanthes polysaccharide and carboxymethyl chitosan accelerates cachectic wound healing and reduces scar hyperplasia 期刊论文
CARBOHYDRATE POLYMERS, 2025, 卷号: 357, 页码: 15
作者:  Chen, Guihua;  Yang, Chenxiao;  Xu, Xingyu;  Yang, Lu;  Zhang, Yingyan;  Cai, Chao;  Muhitdinov, Bahtiyor;  Turaev, Abbaskhan;  Qiu, Hong;  Huang, Shaogang;  Xu, Qin;  Wang, Huiyuan;  Huang, Yongzhuo
收藏  |  浏览/下载：20/0  |  提交时间：2025/04/24
Trichosanthes polysaccharides  Carboxymethyl chitosan  Cancer cachexia  Wound healing  Scar hyperplasia  Engrailed-1  
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:  Zhang, Deyan;  Liu, Lu;  Li, Ming;  Hu, Xinyi;  Zhang, Xi;  Xia, Wenyang;  Wang, Zhen;  Song, Xiaomin;  Huang, Yue;  Dong, Ze;  Yang, Cai-Guang
收藏  |  浏览/下载：13/0  |  提交时间：2025/04/24
RNA modification  N 6-methyladenosine  Demethylase FTO  Structure-activity relationship  Antileukemia  
Proteogenomic characterization of non-functional clinically relevant subgroups 期刊论文
CANCER CELL, 2025, 卷号: 43, 期号: 4, 页码: 36
作者:  Ji, Shunrong;  Cao, Lihua;  Gao, Jing;  Du, Yang;  Ye, Zeng;  Lou, Xin;  Liu, Fen;  Zhang, Yehan;  Xu, Junfeng;  Shi, Xiaohan;  Wang, Huan;  Li, Penghao;  Li, Yikai;  Chen, Hongxu;  Yang, Zhicheng;  Gao, Suizhi;  Zhang, Wuhu;  Huang, Dan;  Ni, Shujuan;  Wei, Miaoyan;  Wang, Fei;  Wang, Yan;  Ding, Tian;  Jing, Desheng;  Fan, Guixiong;  Gong, Zhiyun;  Lu, Renquan;  Qin, Yi;  Chen, Jie;  Xu, Xiaowu;  Wang, Pei;  Zhang, Bing;  Ding, Li;  Robles, Ana I.;  Rodriguez, Henry;  Chang, David K.;  Hruban, Ralph H.;  Gao, Dong;  Gao, Daming;  Jin, Gang;  Zhou, Hu;  Wu, Jianmin;  Yu, Xianjun
收藏  |  浏览/下载：3/0  |  提交时间：2025/06/23
Comparative Study on Covalent and Noncovalent Endogenous Albumin-Binding β-Glucuronidase-Activated SN38 Prodrugs for Antitumor Efficacy 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8361-8376
作者:  Lu, Yingxin;  Jiang, Xing;  Yang, Biyu;  Ding, Mengyuan;  Shen, Yanyan;  Jin, Jiyu;  Yu, Jiahui;  Lu, Wei;  Chen, Yi;  Zhu, Shulei
收藏  |  浏览/下载：6/0  |  提交时间：2025/05/27
Bicyclic polyprenylated acylphloroglucinol-related meroterpenoids as potent DRAK2 inhibitors from Hypericum patulum 期刊论文
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 10
作者:  Huang, Jin-Chang;  Jia, Xin-Yu;  Lv, Yi-Fan;  Xu, Hong-Hong;  Han, Ming;  Yu, Qiang-Qiang;  Lu, Yu-Ting;  Yang, Hong-Xun;  Yang, Yang;  Li, Jing-Ya;  Hou, Ai-Jun
收藏  |  浏览/下载：15/0  |  提交时间：2025/04/01
Hypericum patulum  Hypericaceae  Meroterpenoids  Hyperpatins A-H  Death-associated protein kinase-related  apoptosis-inducing kinase 2  Glucose-stimulated insulin secretion  
Reversing tumor fibrosis for potentiating chemo-immunotherapy via lactic acid exhaustion by codelivery of bicarbonate and JQ1 期刊论文
NANO TODAY, 2025, 卷号: 61, 页码: 16
作者:  Peng, Taoxing;  He, Yihao;  Shao, Xinyue;  Liu, Han;  Yang, Lu;  Xiong, Wei;  Jin, Xiaoying;  Ding, Yang;  Huang, Yongzhuo
收藏  |  浏览/下载：11/0  |  提交时间：2025/04/01
sodium bicarbonate  Nano-adjuvant  Lactic acid exhaustion  Tumor fibrosis reversal  Chemo-immunotherapy  
Time-Dependent Regulation of Sleep-Wakefulness and Electroencephalographic Characteristics by Spontaneous Running in Male Mice 期刊论文
JOURNAL OF SLEEP RESEARCH, 2025, 页码: 16
作者:  Zhou, Wufang;  Zhou, Jialin;  Lu, Qianyu;  Wang, Long;  Liang, Yutao;  Xing, Ye;  Zhang, Zheng;  Yang, Jinshan;  Zhao, Wenxue;  Li, Xin;  Shi, Guangsen
收藏  |  浏览/下载：9/0  |  提交时间：2025/05/27
delta power  spontaneous running  theta wave  voluntary exercise  
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:  Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya;  Wu, Mingfei;  Zhang, Jingyu;  Yin, Hao;  Lu, Yang;  Zhou, Yihui;  Pang, Ao;  Lin, Yushen;  Jiang, Li;  Shi, Qiuqiu;  Geng, Shuangshuang;  Zhou, Yubo;  Yao, Xiaojun;  Li, Linjie;  Duan, Haiting;  Che, Jinxin;  Cao, Ji;  He, Qiaojun;  Dong, Xiaowu
收藏  |  浏览/下载：1/0  |  提交时间：2025/06/23
HDAC7  PROTAC  Selectivity  Hematologic malignancies  Non-enzymatic function  
Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK 期刊论文
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:  Peng, Chang;  Jiang, Haowen;  Jing, Liya;  Yang, Wenhua;  Guan, Xiaotong;  Wang, Hanlin;  Yu, Sike;  Cao, Yutang;  Wang, Min;  Ma, Huan;  Lv, Zan;  Gu, Hongyu;  Xia, Chunmei;  Guo, Xiaozhen;  Sun, Bin;  Wang, Aili;  Xie, Cen;  Wu, Wenbiao;  Lu, Luyiyi;  Song, Jiayi;  Lei, Saifei;  Wu, Rui;  Zang, Yi;  Tang, Erjiang;  Li, Jia
收藏  |  浏览/下载：74/0  |  提交时间：2025/04/01
Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 22
作者:  Liang, Xuewu;  Huang, Yue;  Ren, Hairu;  Liu, Qi;  Chen, Liang;  Zhao, Jiayan;  Gao, Xiangqian;  Lu, Jian;  Yang, Cai-Guang;  Liu, Hong
收藏  |  浏览/下载：27/0  |  提交时间：2025/04/01
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