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Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK 期刊论文
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:  Peng, Chang;  Jiang, Haowen;  Jing, Liya;  Yang, Wenhua;  Guan, Xiaotong;  Wang, Hanlin;  Yu, Sike;  Cao, Yutang;  Wang, Min;  Ma, Huan;  Lv, Zan;  Gu, Hongyu;  Xia, Chunmei;  Guo, Xiaozhen;  Sun, Bin;  Wang, Aili;  Xie, Cen;  Wu, Wenbiao;  Lu, Luyiyi;  Song, Jiayi;  Lei, Saifei;  Wu, Rui;  Zang, Yi;  Tang, Erjiang;  Li, Jia
收藏  |  浏览/下载：70/0  |  提交时间：2025/04/01
Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation 期刊论文
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:  Ren, Jing;  Chen, Xin;  Wang, Hao-yu;  Yang, Tao;  Zhang, Kai-rong;  Lei, Shu-yue;  Qi, Lu-yao;  Feng, Chun-lan;  Zhou, Rong;  Zhou, Hu;  Tang, Wei
收藏  |  浏览/下载：11/0  |  提交时间：2025/04/01
psoriasis  gentiopicroside  keratinocyte  oxidative stress  Keap1-Nrf2 pathway  calcipotriol  
Prediction of Solvate Based on Graph Attention Network 期刊论文
CRYSTAL GROWTH & DESIGN, 2025, 卷号: 25, 期号: 2, 页码: 297-308
作者:  Sun, Shihui;  Wang, Jian-Rong;  Tang, Lei;  Fan, Zhehuan;  Li, Xutong;  Huang, Zifu;  Han, Weizhong;  Wang, Qinggong;  Yu, Jie;  Xie, Zhiyin;  Yang, Wenzhi;  Yang, Zeen;  Zheng, Mingyue;  Wang, Dingyan;  Mei, Xuefeng;  Luo, Xiaomin
收藏  |  浏览/下载：26/0  |  提交时间：2025/04/01
BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair 期刊论文
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:  Chi, Shuaishuai;  Wei, Fan;  Li, Yangsha;  Yu, Lei;  Ma, Chuyao;  Fang, Yanfen;  Yang, Biyu;  Chen, Yi;  Ding, Jian
收藏  |  浏览/下载：63/0  |  提交时间：2025/01/06
CDK4  BRD4  Breast cancer  Protein stability  DNA damage  
YTHDF1 loss in dendritic cells potentiates radiation- induced antitumor immunity via STING-dependent I IFN 期刊论文
JOURNAL OF CLINICAL INVESTIGATION, 2024, 卷号: 134, 期号: 23, 页码: 14
作者:  Wen, Chuangyu;  Wang, Liangliang;  Piffko, Andras;  Chen, Dapeng;  Yu, Xianbin;  Zawieracz, Katarzyna;  Bugno, Jason;  Yang, Kaiting;  Naccasha, Emile Z.;  Ji, Fei;  Wang, Jiaai;  Huang, Xiaona;  Luo, Stephen Y.;  Tan, Lei;  Shen, Bin;  Luo, Cheng;  Mcnerney, Megan E.;  Chmura, Steven J.;  Arina, Ainhoa;  Pitroda, Sean;  He, Chuan;  Liang, Hua Laura;  Weichselbaum, Ralph R.
收藏  |  浏览/下载：17/0  |  提交时间：2025/04/01
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells 期刊论文
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:  Wang, Yingying;  Zhang, Youping;  Luo, Hao;  Wei, Wei;  Liu, Wanting;  Wang, Weiwei;  Wu, Yunzhao;  Peng, Cheng;  Ji, Yanjie;  Zhang, Jianfang;  Zhu, Chujiao;  Bai, Wenhui;  Xia, Li;  Lei, Hu;  Xu, Hanzhang;  Yin, Leimiao;  Weng, Wei;  Yang, Li;  Liu, Ligen;  Zhou, Aiwu;  Wei, Yueyue;  Zhu, Qi;  Zhu, Weiliang;  Yang, Yongqing;  Xu, Zhijian;  Wu, Yingli
收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01
Ubiquitin-specific protease 2  KRAS  Gambogic acid  Multiple myeloma  Degradation  Ubiquitination  Allosteric pocket  Deubiquitination  
Discovery of Thiochroman Derivatives as Potent, Oral Selective Estrogen Receptor Degraders and Antagonists for the Treatment of Endocrine-Resistant Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 23, 页码: 21545-21567
作者:  Zhang, Dan;  Lu, Zhengyu;  He, Yongqi;  Leng, Xin-Yu;  Meng, Xin;  Lei, Xiang;  Kong, Deyu;  Sun, Lulu;  Hu, Wenhao;  Yang, Yushe
收藏  |  浏览/下载：42/0  |  提交时间：2025/01/06
An economically viable stable isotope-enhanced multiple reaction monitoring method for total fatty acid analysis in a mouse model of non-alcoholic fatty liver disease 期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2024, 卷号: 1736, 页码: 10
作者:  Zhang, Zijia;  Liu, Yawen;  Li, Gaohan;  Chen, Xiaoling;  Lei, Min;  Zhou, Yang;  Long, Huali;  Chen, Qinhua;  Hou, Jinjun;  Wu, Wanying
收藏  |  浏览/下载：40/0  |  提交时间：2024/11/26
Stable isotope  Fatty acid  Multiple reaction monitoring  N-dimethylethylenediamine  NAFLD  
The actin-binding protein drebrin disrupts NF2-LATS kinases complex assembly to facilitate liver tumorigenesis 期刊论文
HEPATOLOGY, 2024, 页码: 20
作者:  Sun, Yang;  Wei, Henan;  Yu, Wentao;  Gao, Haoran;  Li, Jinhui;  Li, Xiaoyu;  Zhang, Haijiao;  Zhang, Haoen;  Miao, Sen;  Zhao, Lihua;  Yang, Ruizeng;  Xu, Jinjin;  Lu, Yi;  Wei, Fang;  Zhou, Hu;  Gao, Daming;  Jin, Yunyun;  Zhang, Lei
收藏  |  浏览/下载：43/0  |  提交时间：2024/11/05
A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy 期刊论文
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 18
作者:  Gao, Jing;  Jiang, Xingyu;  Lei, Shumin;  Cheng, Wenhao;  Lai, Yi;  Li, Min;  Yang, Lei;  Liu, Peifeng;  Chen, Xiao-hua;  Huang, Min;  Yu, Haijun;  Xu, Huixiong;  Xu, Zhiai
收藏  |  浏览/下载：26/0  |  提交时间：2024/09/26
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