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Prediction of Solvate Based on Graph Attention Network 期刊论文
CRYSTAL GROWTH & DESIGN, 2025, 卷号: 25, 期号: 2, 页码: 297-308
Authors:  Sun, Shihui;  Wang, Jian-Rong;  Tang, Lei;  Fan, Zhehuan;  Li, Xutong;  Huang, Zifu;  Han, Weizhong;  Wang, Qinggong;  Yu, Jie;  Xie, Zhiyin;  Yang, Wenzhi;  Yang, Zeen;  Zheng, Mingyue;  Wang, Dingyan;  Mei, Xuefeng;  Luo, Xiaomin
Favorite  |  View/Download：26/0  |  Submit date：2025/04/01
Phosphinothio(seleno)ation of alkynes/olefins and application on the late-stage functionalization of natural products 期刊论文
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 290
Authors:  Shao, Chang-Wei;  Wan, Pei-Feng;  Xu, Quan;  Yang, Ze-Nan;  Geng, Mei-Yu;  Zhang, Yu;  Zhang, Xing-Hua;  Li, Xu-Wen
Favorite  |  View/Download：1/0  |  Submit date：2025/06/04
Sodium oligomannate disrupts the adherence of Ribhigh bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice 期刊论文
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
Authors:  Wang, Xinyi;  Xie, Zuoquan;  Yuan, Jie;  Jin, Enjing;  Lian, Wen;  Chang, Shuaishuai;  Sun, Guangqiang;  Feng, Zhengnan;  Xu, Hui;  Du, Chen;  Yang, Xinying;  Xia, Aihua;  Qiu, Ji;  Zhang, Qingli;  Lin, Feifei;  Liu, Jia;  Li, Liang;  Du, Xiaoguang;  Xiao, Zhongping;  Yi, Zhou;  Luo, Zhiyu;  Ge, Changrong;  Li, Rui;  Zheng, Mingyue;  Jiang, Yi;  Wang, Tao;  Zhang, Jing;  Guo, Qihao;  Geng, Meiyu
Favorite  |  View/Download：33/0  |  Submit date：2024/12/16
Mass balance, metabolism, and pharmacokinetics of [14C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers 期刊论文
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
Authors:  Zhao, Chun-Yang;  Zhang, Li-Jun;  Sun, Chan;  Yu, Cheng-Yin;  Wang, Jian;  Sai, Yang;  Su, Wei-Guo;  Chen, Qian;  Wang, Wei;  Jia, Jing-Ying;  Liu, Gang-Yi;  Liu, Yan-Mei
Favorite  |  View/Download：59/0  |  Submit date：2025/01/06
amdizalisib  PI3K delta kinase  metabolism  mass balance  metabolite identification  pharmacokinetics  safety  
A DXd/TLR7-Agonist Dual-Conjugate Anti-HER2 ADC Exerts Robust Antitumor Activity Through Tumor Cell Killing and Immune Activation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2024, 卷号: 23, 期号: 11, 页码: 1639-1651
Authors:  Yue, Hangtian;  Xu, Hui;  Ma, Lanping;  Li, Xiyuan;  Yang, Biyu;  Wang, Xiyuan;  Zeng, Qingzhong;  Li, Han;  Zhang, Deqiang;  Geng, Meiyu;  Meng, Tao;  Xie, Zuoquan
Favorite  |  View/Download：36/0  |  Submit date：2024/12/11
Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 18
Authors:  Xie, Zuoquan;  Zhou, Qinming;  Hu, Jin;  He, Lu;  Meng, Huangyu;  Liu, Xiaoni;  Sun, Guangqiang;  Luo, Zhiyu;  Feng, Yuan;  Li, Liang;  Chu, Xingkun;  Du, Chen;  Yang, Dabing;  Yang, Xinying;  Zhang, Jing;  Ge, Changrong;  Zhang, Xiang;  Chen, Sheng;  Geng, Meiyu
Favorite  |  View/Download：23/0  |  Submit date：2024/12/11
Neuromyelitis optica spectrum disorders  Blood immune cells phenotyping  Plasma cytokine array  Plasma metabolomics  Biomarker  
Circulating metabolites of Borneolum syntheticum (Bingpian) ameliorate atherosclerosis in ApoE-/- mice via inhibiting macrophage foam-cell formation 期刊论文
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 18
Authors:  He, Rong-rong;  Ma, Chuan-rui;  He, Xin;  Dong, Yan-xi;  Li, Hui;  Chu, Zi-xuan;  Yang, Xi-he;  Wang, Jia-qi;  Wang, Ting;  Wang, Feng-qing;  Du, Fei-fei;  Rao, Ying;  Yu, Wen-xuan;  Gao, Xiu-mei;  Fan, Guan-wei;  Cheng, Chen;  Li, Chuan
Favorite  |  View/Download：96/0  |  Submit date：2024/11/26
Borneolum syntheticum  Bingpian  borneol  isoborneol  metabolism  atherosclerosis  
13,14-seco seco withaphysalins from Physalis minima and their inhibitory effects on NLRP3 inflammasome activation 期刊论文
BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 12
Authors:  Hu, Bintao;  Peng, Xia;  Tang, Chunping;  Geng, Meiyu;  Yao, Sheng;  Ai, Jing;  Ye, Yang
Favorite  |  View/Download：85/0  |  Submit date：2024/09/26
Physalis minima  NLRP3  Anti-inflammatory  13,14-seco withaphysalin  
19F qNMR based pharmacokinetics, metabolism and mass balance studies of SARS-CoV-2-3CL protease inhibitor simnotrelvir (SIM0417) in humans 期刊论文
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
Authors:  Wang, Ze-yu;  Ren, Yong-mei;  Hu, Shu-wei;  Zhang, Nai-xia;  Dong, Meng-xiao;  Li, Yun;  Yang, Yang;  Guo, Zi-jia;  Xu, Shan-sen;  Chen, Jia;  Goh, Aik Han;  Chen, Xiao-yan
Favorite  |  View/Download：93/0  |  Submit date：2024/11/05
COVID-19  simnotrelvir  F-19 qNMR  pharmacokinetics  metabolism  mass balance.  
GV-971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities 期刊论文
CNS NEUROSCIENCE & THERAPEUTICS, 2024, 卷号: 30, 期号: 7, 页码: 15
Authors:  Yang, Xinying;  Zhangyi, Zhongheng;  Yu, Aisong;  Zhou, Qinming;  Xia, Aihua;  Qiu, Ji;  Cai, Meixiang;  Chu, Xingkun;  Li, Liang;  Feng, Zhengnan;  Luo, Zhiyu;  Sun, Guangqiang;  Zhang, Jing;  Geng, Meiyu;  Chen, Sheng;  Xie, Zuoquan
Favorite  |  View/Download：50/0  |  Submit date：2024/08/22
gut microbiota  GV-971  neuroinflammation  Neuromyelitis optica spectrum disorders  NMO-IgG  
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