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Undescribed Phyllocladane-Type Diterpenoids from Callicarpa giraldii Hesse ex Rehd. and Their Anti-Neuroinflammatory Activity 期刊论文
MOLECULES, 2025, 卷号: 30, 期号: 7, 页码: 27
作者:  Liang, Xu;  Gong, Qi;  Xu, Yuting;  Mu, Jiaxing;  Tang, Chunping;  Hu, Bintao;  Ke, Changqiang;  Yao, Sheng;  Zhang, Haiyan;  Ye, Yang
收藏  |  浏览/下载：15/0  |  提交时间：2025/05/27
Callicarpa giraldii  phyllocladane-type diterpenoids  anti-neuroinflammatory activity  calligirlins A-R  
Uncommon Diterpenoids with Diverse Frameworks from the South China Sea Sponge Spongia officinalis and Their Anti-inflammatory Activities 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2025, 卷号: 90, 期号: 5, 页码: 1950-1956
作者:  Li, Song-Wei;  Liu, Jiao;  Liu, Zi-Yi;  Fu, Yan;  Yao, Li-Gong;  Gu, Yu-Cheng;  Zhang, Hai-Yan;  Li, Xu-Wen;  Guo, Yue-Wei
收藏  |  浏览/下载：7/0  |  提交时间：2025/04/01
FMP-6-S4 impeded Aβ42 induced SH-SY5Y cell injury by targeting cyclophilin D 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2024, 卷号: 119, 页码: 9
作者:  Gao, Pengcheng;  Li, Saijuan;  Wang, Yuyong;  Wu, Fangge;  Jin, Can;  Zhao, Danfeng;  Zhang, Haiyan;  Liao, Wenfeng;  Ding, Kan
收藏  |  浏览/下载：41/0  |  提交时间：2024/11/05
Alzheimer's disease  Fructus Mori  Amyloid beta  Cyclophilin D  Mitochondrial permeability transition pore  Glycopeptide  
ABBV-744 alleviates LPS-induced neuroinflammation via regulation of BATF2-IRF4-STAT1/3/5 axis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:  Wang, Le-le;  Wang, Huan;  Lin, Si-jin;  Xu, Xing-yu;  Hu, Wen-juan;  Liu, Jia;  Zhang, Hai-yan
收藏  |  浏览/下载：60/0  |  提交时间：2024/07/12
microglial inflammation  BD2  ABBV-744  BATF2  IRF4  JAK/STAT  
Anti-inflammatory Steroids from the South China Sea Sponge Spongia officinalis 期刊论文
CHEMISTRY & BIODIVERSITY, 2024, 页码: 5
作者:  Liu, Jiao;  Liu, Zi-Yi;  Fu, Yan;  Gu, Yu-Cheng;  Li, Song-Wei;  Zhang, Hai-Yan;  Guo, Yue-Wei
收藏  |  浏览/下载：76/0  |  提交时间：2024/05/31
Sponge  Spongia officinalis  Chemical investigation  Absolute configuration  Anti-inflammatory activity  
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease 期刊论文
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:  Wu, Xiuyuan;  Ze, Xiaotong;  Qin, Shuai;  Zhang, Beiyu;  Li, Xinnan;  Gong, Qi;  Zhang, Haiyan;  Zhu, Zheying;  Xu, Jinyi
收藏  |  浏览/下载：80/0  |  提交时间：2024/06/27
Alzheimer's disease  tacrine  cystamine  MTDLs  inhibitors  molecular modeling  
A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文
RSC MEDICINAL CHEMISTRY, 2024, 页码: 9
作者:  Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng;  Xiang, Huaijiang;  Hu, Youhong;  Zhang, Haiyan
收藏  |  浏览/下载：58/0  |  提交时间：2024/05/07
JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 258-267
作者:  Tao, Lingxue;  Yu, Weichen;  Liu, Ziyi;  Zhao, Danfeng;  Lin, Sijin;  Szaloki, Dora;  Kicsak, Mate;  Kurtan, Tibor;  Zhang, Haiyan
收藏  |  浏览/下载：60/0  |  提交时间：2024/02/27
neuroinflammation  microglia  LPS  JAK/STAT  Nrf2  
Progress and Gaps in Respiratory Disease Research and Treatment: Highlights of the IRM 2024 in Shanghai 期刊论文
Journal of respiratory biology and translational medicine, 2024, 卷号: 1, 期号: 4, 页码: 10021
作者:  Zhang, Jin-San;  Dhlamini, Qhaweni;  Guo, Qiang;  Quan, Meiyu;  Wu, Jin;  Lyu, Handeng;  Chong, Lei;  Lv, Yuqing;  Lin, Yuting;  Zhou, Bin;  Liu, Yuru;  Ji, Honglong;  Lin, Xinhua;  Ning, Wen;  Sui, Pengfei;  Chen, Huaiyong;  Gao, Peisong;  Chen, Wei;  Zhou, Xiaobo;  Song, Yuanlin;  Wang, Chaoqun;  Su, Xiao;  Xu, Jinfu;  Sun, Jie;  Chen, Yin;  Geng, Yan;  Song, Hai;  Ji, Hongbin;  Di, Yuanpu Peter;  Tang, Hao;  Lu, Chao;  Li, Jinghong;  Cheng, Ke;  Cao, Mengshu;  Liang, Jiurong;  Zhang, Yingze;  Zhou, Yang;  Xi, Ying;  Xiong, Weining;  Cao, Bin;  Que, Jianwen;  Jiang, Dianhua
收藏  |  浏览/下载：21/0  |  提交时间：2025/06/04
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan;  Peng, Shao-Ping;  Yang, Yu-Mei;  Shu, Pan;  Li, Pei-Jin;  Li, Shan;  Hu, Hong-Lin;  Li, Qian;  Song, Lin-Lin;  Chen, Ke-Guang;  Zhou, Hai-Yan;  Zhang, Ye-Hui;  Zhao, Fu-Rong;  Tang, Bo-Hao;  Zhang, Wei;  Zhang, Xin-Fang;  Fu, Shu-Meng;  Hao, Guo-Xiang;  Zheng, Yi;  Shen, Jing-Shan;  Xu, Ye-Chun;  Jiang, Xiang-Rui;  Zhang, Lei-Ke;  Tang, Ren-Hong;  Zhao, Wei
收藏  |  浏览/下载：68/0  |  提交时间：2023/12/11
COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects  
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