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中国科学院上海药物研究所机构知识库
Knowledge Management System of Shanghai Institute of Materia Medica, CAS
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Huang, Wei [4]
Liu, Zhi [4]
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Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
Authors:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
;
Lai, Yi
;
Zhang, Fan
;
Wagner, Ernst
;
Yu, Hai-jun
;
Chen, Xiao-hua
;
Xu, Zhi-ai
Favorite
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View/Download:43/0
|
Submit date:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Site- and Stereoselective Glycomodification of Biomolecules through Carbohydrate-Promoted Pictet-Spengler Reaction
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 页码: 11
Authors:
Liu, Bo
;
Zou, Xiangman
;
Zhang, Yue
;
Yang, Yang
;
Xu, Hao
;
Tang, Feng
;
Yu, Huixin
;
Xia, Fei
;
Liu, Zhi
;
Zhao, Jianwei
;
Shi, Wei
;
Huang, Wei
Favorite
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View/Download:33/0
|
Submit date:2024/05/07
Recent advances in antibody glycoengineering for the of functions
期刊论文
CURRENT OPINION IN CHEMICAL BIOLOGY, 2024, 卷号: 78, 页码: 10
Authors:
Liu, Zhi
;
Zou, Xiangman
;
Tang, Feng
;
Huang, Wei
Favorite
|
View/Download:41/0
|
Submit date:2024/03/06
Antibody glycoengineering
Endoglycosidase
Chemo-enzymatic
Glycosyltransferase
Antibody-drug conjugates
Enhanced antibody-defucosylation capability of a-L-fucosidase by proximity-based protein fusion
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 645, 页码: 40-46
Authors:
Fan, Shuquan
;
Li, Wanzhen
;
Zhang, Kuixing
;
Zou, Xiangman
;
Shi, Wei
;
Liu, Zhi
;
Tang, Caihong
;
Huang, Wei
;
Tang, Feng
Favorite
|
View/Download:80/0
|
Submit date:2023/04/10
Tumor-Targeted Theranostic Probe for Near Infrared II Window Fluorescence Imaging and Anticancer Therapy of Triple-Negative Breast Cancer
期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2022, 卷号: 50, 期号: 6, 页码: 912-923
Authors:
Zou Zhi-Feng
;
Gao Jing
;
Lai Yi
;
Xu Zhi-Ai
Favorite
|
View/Download:56/0
|
Submit date:2022/08/16
Active targeting
Near infrared II region fluorescence
Photothermal therapy
Theranostic
Triple negative breast cancer
Enhanced transglycosylation activity of an Endo-F3 mutant by ligand-directed localization
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 页码: 10
Authors:
Zou, Xiangman
;
Liu, Zhi
;
Liu, Liya
;
Shi, Wei
;
Li, Wanzhen
;
Guo, Zifen
;
Tang, Feng
;
Huang, Wei
Favorite
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View/Download:73/0
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Submit date:2022/06/15
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
Authors:
Wang, Zhen
;
Jiang, Xiangrui
;
Zhang, Xianglei
;
Tian, Guanghui
;
Yang, Rulei
;
Wu, Jianzhong
;
Zou, Xiaoli
;
Liu, Zheng
;
Yang, Xiaojun
;
Wu, Chunhui
;
Shi, Jing
;
Li, Jianfeng
;
Suo, Jin
;
Wang, Yu
;
Zhang, Rongxia
;
Xu, Zhijian
;
Gong, Xudong
;
He, Yang
;
Zhu, Weiliang
;
Aisa, Haji Akber
;
Jiang, Hualiang
;
Xu, Yechun
;
Shen, Jingshan
Favorite
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View/Download:70/0
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Submit date:2020/07/01
Facile Synthesis of 7-epi-Taxane and Its Derivatives and Preliminary Evaluation of Anticancer Activity
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2016, 卷号: 34, 期号: 11, 页码: 1165-1176
Authors:
Li, Zhao
;
Feng, Jia
;
Zou, Kun
;
Yang, Zhuo
;
Zhang, Yong
;
Xu, Zhijian
;
Li, Bo
;
Shi, Jiye
;
Li, Yiming
;
Zhu, Weiliang
;
Chen, Kaixian
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View/Download:73/0
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Submit date:2019/01/08
taxane
7-epi-taxane
silver oxide
amino acid
C-13 derivative of taxane
anticancer activity
Intestinally-targeted TGR5 agonists equipped with quaternary ammonium have an improved hypoglycemic effect and reduced gallbladder filling effect
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
Authors:
Cao, Hua
;
Chen, Zhi-Xiang
;
Wang, Kai
;
Ning, Meng-Meng
;
Zou, Qing-An
;
Feng, Ying
;
Ye, Yang-Liang
;
Leng, Ying
;
Shen, Jian-Hua
Favorite
|
View/Download:46/0
|
Submit date:2019/01/08
气质联用仪技术体外评价硫酸铜解毒杀虫单的研究
期刊论文
中国卫生检验杂志, 2007, 期号: 07, 页码: 1170-1172+1175
Authors:
魏锋
;
蒋志华
;
彭云
;
邹汉军
Favorite
|
View/Download:35/0
|
Submit date:2019/01/08
硫酸铜
杀虫单
气质联用仪
SPSS
正交实验设计
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