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Harnessing nuclear receptors to modulate hepatic stellate cell activation for liver fibrosis resolution 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 232, 页码: 15
作者:  Sun, Yaxin;  Yuan, Xiaoyan;  Hu, Zhenhua;  Li, Yuanyuan
收藏  |  浏览/下载:19/0  |  提交时间:2025/04/01
Nuclear receptors  Hepatic stellate cell  Liver fibrosis  MASH  MAFLD  Resmetirom  
Peptidoglycan isolated from the fruit of Lycium barbarum alleviates liver fibrosis in mice by regulating the TGF-β/Smad7 signaling and gut microbiota 期刊论文
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:  Nie, Ying-min;  Zhou, Wan-qi;  Niu, Ting;  Mao, Meng-fei;  Zhan, Yu-xue;  Li, Yun;  Wang, Kai-ping;  Li, Mei-xia;  Ding, Kan
收藏  |  浏览/下载:8/0  |  提交时间:2025/04/01
liver fibrosis  Lycium barbarum  peptidoglycan  LBPW  TGF-beta/Smad7  Akkermansia muciniphila  
A novel pectin-like polysaccharide from Crocus sativus targets Galectin-3 to inhibit hepatic stellate cells activation and liver fibrosis 期刊论文
CARBOHYDRATE POLYMERS, 2025, 卷号: 348, 页码: 16
作者:  Tang, Bixi;  Jin, Can;  Li, Maoting;  Liu, Siqi;  Zhang, Xuemei;  Li, Jia;  Ding, Kan;  Zang, Yi
收藏  |  浏览/下载:37/0  |  提交时间:2024/12/11
Liver fibrosis  Galectin 3  Pectin  Polysaccharide structure  Hepatic stellate cell  
The structure elucidation and alleviating effect on liver fibrosis in vivo of pectin-like polysaccharide isolated from Buddleja officinalis 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 284, 页码: 14
作者:  Zong, Jianing;  Li, Yun;  Zhou, Wanqi;  Mao, Mengfei;  Xu, Xin;  Cai, Simin;  Li, Meixia;  Ding, Kan
收藏  |  浏览/下载:46/0  |  提交时间:2025/01/14
Buddleja officinalis  Polysaccharides  Pectin  Liver fibrosis  
Design and Synthesis of Dual Galectin-3 and EGFR Inhibitors Against Liver Fibrosis 期刊论文
CHEMISTRY-AN ASIAN JOURNAL, 2024, 页码: 14
作者:  Liu, Shuanglin;  He, Fei;  Jin, Can;  Li, Qing;  Zhao, Guilong;  Ding, Kan
收藏  |  浏览/下载:32/0  |  提交时间:2024/12/25
Galectin-3  EGFR  Inhibitor  Synthesis  Liver fibrosis  
A novel experimental mouse model of diabetic nonalcoholic steatohepatitis: A critical role for acid-sensitive Ion Channel 1a 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 178, 页码: 15
作者:  Hu, Xiaojie;  Lin, Huimin;  Qian, Shengying;  Xu, Zhou;  Li, Zihao;  Qian, Shishun;  Yang, Furong;  Hou, Hui;  Xie, Qinxiu;  Wu, Wenyong;  Hu, Chengmu;  Abou-Elnour, Amira;  He, Yong;  Huang, Yan
收藏  |  浏览/下载:90/0  |  提交时间:2024/10/09
ASIC1a  FPC  Liver fibrosis  NASH  T2DM  
Luteolin-7-diglucuronide, a novel PTP1B inhibitor, ameliorates hepatic stellate cell activation and liver fibrosis in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:  Tang, Bi-xi;  Zhang, Yong;  Sun, Dan-dan;  Liu, Qin-yi;  Li, Cong;  Wang, Pei-pei;  Gao, Li-xin;  Zhang, Xue-mei;  Li, Jia;  Zhu, Wei-liang;  Zang, Yi
收藏  |  浏览/下载:40/0  |  提交时间:2024/09/26
liver fibrosis  phytochemical  luteolin 7-diglucuronide  HSC activation  PTP1B  
Enhanced In Vitro Efficacy of Verbascoside in Suppressing Hepatic Stellate Cell Activation via ROS Scavenging with Reverse Microemulsion 期刊论文
ANTIOXIDANTS, 2024, 卷号: 13, 期号: 8, 页码: 18
作者:  Xiao, Xiao;  Yang, Feiyu;  Huang, Yuling;  Liu, Shaohui;  Hu, Zhenhua;  Liao, Shanggao;  Li, Yuanyuan
收藏  |  浏览/下载:25/0  |  提交时间:2024/10/21
liver fibrosis  verbascoside  hepatic stellate cells  reverse microemulsion  antioxidants  
Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 卷号: 974, 页码: 10
作者:  Lv, Mengjia;  Chen, Shiyi;  Shan, Mengwen;  Si, Yuan;  Huang, Chenggang;  Chen, Jing;  Gong, Likun
收藏  |  浏览/下载:140/0  |  提交时间:2024/07/12
Liver fibrosis  Arctigenin  Hepatic stellate cell (HSC)  AMPK  PPAR gamma  
Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway 期刊论文
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:  Meng, Qian;  Zhu, Hongwen;  Li, Yuanyuan;  Peng, Xiaotian;  Wang, Tianming;  Huang, Hui;  Zhou, Hu;  Liu, Yuejia;  Ru, Sujie;  Wu, Jiasheng;  Ma, Yueming
收藏  |  浏览/下载:53/0  |  提交时间:2024/05/07
Yinchenzhufu decoction  proteomics  cholestasis  liver fibrosis  PDGFR beta/PI3K/AKT  
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